Every tool your trial needs.
Nothing it doesn't.
Six integrated modules replace your CTMS, signal monitoring, recruitment platform, and half your spreadsheets. Each one is AI-native — not a legacy tool with AI bolted on.
Swarm Simulations
Monte Carlo simulations powered by LLM reasoning agents. Model enrollment scenarios, budget allocation, and competitive dynamics before recruiting a single patient. Each agent maintains its own mental model of site behavior, adjusting predictions based on historical data, weather patterns, and regional demographics.
- 10,000+ scenarios per simulation run
- 6 specialized agent roles per site
- Overnight autoresearch self-optimization
- Backtest against historical ground truth
- Budget and timeline sensitivity analysis
Intelligence Engine
Continuous signal ingestion from seven sources, processed by a multi-tier AI pipeline. Entity extraction, relevance scoring, classification, and sentiment analysis transform raw data into actionable intelligence. Breaking alerts surface safety signals days before formal reports.
- ClinicalTrials.gov — trial activation, competitor moves
- FDA — guidance updates, warning letters, approvals
- PubMed — publication signals, endpoint precedent
- X.com — investigator sentiment, site reputation
- FAERS — adverse event signal detection (2.3x threshold)
- eCFR — regulatory changes, compliance updates
- Weather Intelligence — site accessibility, enrollment impact
TrialClaw Site Agents
A distributed network of seven specialized AI agents deployed at every clinical site. Each agent operates autonomously with cross-role observation sharing, making real-time decisions about screening, scheduling, risk, supply, compliance, and coordination. Regional head agents aggregate site-level intelligence.
- INTAKE — patient screening and eligibility verification
- RECRUITER — enrollment optimization and outreach
- SCHEDULER — visit management and calendar coordination
- WATCHDOG — risk flagging and anomaly detection
- QUARTERMASTER — supply chain and inventory management
- DISPATCH — inter-site coordination and load balancing
- GUARDIAN — regulatory compliance monitoring
Digital Twins
Non-PII synthetic patient cohorts built from trial demographics and regional health data. Test protocol changes, predict enrollment bottlenecks, and optimize site selection without touching real patient data. Digital twins learn from each simulation run, improving fidelity over time.
- Zero PII — fully synthetic cohort generation
- Protocol amendment impact testing
- Site selection optimization with catchment analysis
- Enrollment bottleneck prediction
- Demographic distribution modeling
Predictive Analytics & Prediction Markets
Internal prediction markets let stakeholders bet on enrollment milestones, creating a collective intelligence layer that outperforms individual forecasts. Combined with AI-driven predictive models, Trial Foundry delivers enrollment timeline estimates with confidence intervals.
- Enrollment timeline confidence intervals
- Site performance ranking and prediction
- Competitive landscape trajectory modeling
- Budget burn-rate forecasting
- Internal prediction market for milestone estimation
Compliance & GUARDIAN
The GUARDIAN regulatory agent monitors compliance across seven jurisdictions in real time. Automated protocol deviation detection, SAE/SUSAR tracking, IRB submission management, and a complete audit trail. Built on ICH-GCP guidelines with GDPR and HIPAA compliance built in.
- FDA, EMA, PMDA, ANVISA, TGA, NMPA, CDSCO coverage
- Automated protocol deviation detection
- SAE/SUSAR tracking and reporting
- IRB submission workflow management
- GDPR and HIPAA compliance verification
- 100% immutable audit trail